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[DOI] [PubMed] [Google Scholar] 16.Hurren KM, Pinelli NR

We used a one-pot deprotection-coupling methodology 20,21 where an optimized amount of deprotection base could be added directly to the post-coupling solution without any draining, this allows for the reuse of both solvent and heat from the coupling solution to facilitate the deprotection process resulting in further solvent and time savings

However, this can be tricky if nausea disrupts sleep or causes you to skip meals the next morning